Baker, Ruth E. and Schnell, S. and Maini, P. K. (2009) Waves and patterning in developmental biology: vertebrate segmentation and feather bud formation as case studies. International Journal of Developmental Biology, 53 (5/6). pp. 783-794.
|PDF - Accepted Version|
Official URL: http://www.ijdb.ehu.es/web/paper.php?doi=072493rb
In this article we will discuss the integration of developmental patterning mechanisms with waves of competency that control the ability of a homogeneous field of cells to react to pattern forming cues and generate spatially heterogeneous patterns. We base our discussion around two well known patterning events that take place in the early embryo: somitogenesis and feather bud formation. We outline mathematical models to describe each patterning mechanism, present the results of numerical simulations and discuss the validity of each model in relation to our example patterning processes.
|Uncontrolled Keywords:||developmental waves, patterning mechanisms, mathematical modelling, somitogenesis|
|Subjects:||A - C > Biology and other natural sciences|
|Research Groups:||Centre for Mathematical Biology|
|Deposited By:||Philip Maini|
|Deposited On:||30 Jun 2009 07:17|
|Last Modified:||20 Jul 2009 14:24|
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