The Mathematical Institute, University of Oxford, Eprints Archive

A biomimetic algorithm for the improved detection of microarray features,

Nicolau jr, D. V. and Nicolau, D. V. and Maini, P. K. (2007) A biomimetic algorithm for the improved detection of microarray features,. In Imaging, Manipulation, and Analysis of Biomolecules, Cells and Tissues V, 64411C (n/a). The International Society for Optical Engineering, USA. ISBN 10.1117/12.725769

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Abstract

One the major difficulties of microarray technology relate to the processing of large and - importantly - error-loaded images of the dots on the chip surface. Whatever the source of these errors, those obtained in the first stage of data acquisition - segmentation - are passed down to the subsequent processes, with deleterious results. As it has been demonstrated recently that biological systems have evolved algorithms that are mathematically efficient, this contribution attempts to test an algorithm that mimics a bacterial-"patented" algorithm for the search of available space and nutrients to find, "zero-in" and eventually delimitate the features existent on the microarray surface.

Item Type:Book
Additional Information:n/a
Uncontrolled Keywords:n/a
Subjects:A - C > Biology and other natural sciences
Research Groups:Centre for Mathematical Biology
ID Code:587
Deposited By:Philip Maini
Deposited On:17 Apr 2007
Last Modified:08 Oct 2012 14:03

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