Maini, P. K. and Alarcon, T. and Byrne, H. M. and Owen, M. R. and Murphy, J. (2007) Structural adaptation in normal and cancerous vasculature. In: In: MathEverywhere: Deterministic and Stochastic Modelling in Biomedicine, Economics and Industry. Springer, Berlin, Germany, pp. 165-178. ISBN 3-540-44445-9
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The dynamics of cancerous tissue growth involves the complex interaction of a number of phenomena interacting over a range of temporal and spatial scales. While several processes involved have been studied, the adaptation of the vasculature within a growing tumour has thus far received little attention. We consider a hybrid cellular automaton model which analyses the interaction between the tumour vascular network and tissue growth. We compute the temporal behaviour of the cancerous cell population under different hypotheses of structural adaptation in the vasculature. This may provide a possible method of determining experimentally which adaptation mechanisms are at work.
|Item Type:||Book Section|
|Subjects:||A - C > Biology and other natural sciences|
|Research Groups:||Centre for Mathematical Biology|
|Deposited By:||Philip Maini|
|Deposited On:||25 Mar 2007|
|Last Modified:||29 May 2015 18:24|
Available Versions of this Item
Structural adaptation in normal and cancerous vasculature. (deposited 21 Mar 2007)
Structural adaptation in normal and cancerous vasculature. (deposited 22 Mar 2007)
- Structural adaptation in normal and cancerous vasculature. (deposited 25 Mar 2007) [Currently Displayed]
- Structural adaptation in normal and cancerous vasculature. (deposited 22 Mar 2007)
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