Perelson, A. S. and Maini, P. K. and Murray, J. D. and Hyman, J. M. and Oster, G. F. (1986) Nonlinear pattern selection in a mechanical model for morphogenesis. Journal of Mathematical Biology, 24 (5). pp. 525-541.
We present a numerical study of the nonlinear mechanical model for morphogenesis proposed by Oster et al. (1983) with the aim of establishing the pattern forming capability of the model. We present a technique for mode selection based on linear analysis and show that, in many cases, it is a reliable predictor for nonlinear mode selection. In order to determine the set of model parameters that can generate a particular pattern we develop a technique based on nonlinear least square fitting to a dispersion relation. As an application we present a scenario for sequential pattern formation of dermal aggregations in chick embryos which leads to the hexagonal array of cell aggregations observed in feather germ formation in vivo.
|Subjects:||A - C > Biology and other natural sciences|
|Research Groups:||Centre for Mathematical Biology|
|Deposited By:||Philip Maini|
|Deposited On:||15 Dec 2006|
|Last Modified:||20 Jul 2009 14:22|
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