Chaplain, M. A. J. and Benson, D. L. and Maini, P. K. (1994) Nonlinear diffusion of a growth inhibitory factor in multicell spheriods. Mathematical Biosciences, 121 (1). pp. 1-13.
A mathematical model is presented for the production of a growth inhibitory factor (GIF) within a multicell spheroid. The model is based on the assumption that the GIF diffuses within the spheroid in a nonlinear spatially dependent manner. This is in contrast with previous models, in which the nonlinearity was assumed in the production team. The results of the new model are compared with those of previous models and with experimental data.
|Subjects:||A - C > Biology and other natural sciences|
|Research Groups:||Centre for Mathematical Biology|
|Deposited By:||Philip Maini|
|Deposited On:||12 Dec 2006|
|Last Modified:||29 May 2015 18:23|
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