Kulesa, P. M. and Cruywagen, G. C. and Lubkin, S. R. and Maini, P. K. and Sneyd, J. S. and Ferguson, M. W. J. and Murray, J. D. (1996) On a model mechanism for the spatial patterning of teeth primordia in the Alligator. Journal of Theoretical Biology, 180 (4). pp. 287-296.
We propose a model mechanism for the initiation and spatial positioning of teeth primordia in the alligator,Alligator mississippiensis. Detailed embryological studies by Westergaard & Ferguson (1986, 1987, 1990) show that jaw growth plays a crucial role in the developmental patterning of the tooth initiation process. Based on biological data we develop a reaction-diffusion mechanism, which crucially includes domain growth. The model can reproduce the spatial pattern development of the first seven teeth primordia in the lower half jaw ofA. mississippiensis. The results for the precise spatio-temporal sequence compare well with detailed developmental experiments.
|Subjects:||A - C > Biology and other natural sciences|
|Research Groups:||Centre for Mathematical Biology|
|Deposited By:||Philip Maini|
|Deposited On:||10 Dec 2006|
|Last Modified:||08 Oct 2012 14:35|
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