The Mathematical Institute, University of Oxford, Eprints Archive

On a model mechanism for the spatial patterning of teeth primordia in the Alligator

Kulesa, P. M. and Cruywagen, G. C. and Lubkin, S. R. and Maini, P. K. and Sneyd, J. S. and Ferguson, M. W. J. and Murray, J. D. (1996) On a model mechanism for the spatial patterning of teeth primordia in the Alligator. Journal of Theoretical Biology, 180 (4). pp. 287-296.

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Abstract

We propose a model mechanism for the initiation and spatial positioning of teeth primordia in the alligator,Alligator mississippiensis. Detailed embryological studies by Westergaard & Ferguson (1986, 1987, 1990) show that jaw growth plays a crucial role in the developmental patterning of the tooth initiation process. Based on biological data we develop a reaction-diffusion mechanism, which crucially includes domain growth. The model can reproduce the spatial pattern development of the first seven teeth primordia in the lower half jaw ofA. mississippiensis. The results for the precise spatio-temporal sequence compare well with detailed developmental experiments.

Item Type:Article
Uncontrolled Keywords:n/a
Subjects:A - C > Biology and other natural sciences
Research Groups:Centre for Mathematical Biology
ID Code:470
Deposited By:Philip Maini
Deposited On:10 Dec 2006
Last Modified:08 Oct 2012 14:35

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