Schnell, S. and Maini, P. K. (2002) Enzyme kinetics far from the standard quasisteadystate and equilibrium approximations. Mathematical and Computer Modelling, 35 (12). pp. 137144.

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Abstract
Analytic approximations of the timeevolution of the single enzymesubstrate reaction are valid for all but a small region of parameter space in the positive initial enzymeinitial substrate concentration plane. We find velocity equations for the substrate decomposition and product formation with the aid of the total quasisteadystate approximation and an aggregation technique for cases where neither the more normally employed standard nor reverse quasisteadystate approximations are valid. Applications to determining reaction kinetic parameters are discussed.
Item Type:  Article 

Uncontrolled Keywords:  Total quasisteadystate approximation; Fitting procedure; Aggregation technique; Singular perturbation 
Subjects:  A  C > Biology and other natural sciences 
Research Groups:  Centre for Mathematical Biology 
ID Code:  400 
Deposited By:  Philip Maini 
Deposited On:  20 Nov 2006 
Last Modified:  29 May 2015 18:21 
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