The Mathematical Institute, University of Oxford, Eprints Archive

Models, measurement & inference in epithelial tissue dynamics

Maclaren, O J and Byrne, H. M. and Maini, P. K. and Fletcher, A G (2015) Models, measurement & inference in epithelial tissue dynamics. Mathematical Biosciences & Engineerig, 12 (6). pp. 1321-1340.

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Abstract

The majority of solid tumours arise in epithelia and therefore much research effort has gone into investigating the growth, renewal and regulation of these tissues. Here we review different mathematical and computational approaches that have been used to model epithelia. We compare different models and describe future challenges that need to be overcome in order to fully exploit new data which present, for the first time, the real possibility for detailed model validation and comparison.

Item Type:Article
Uncontrolled Keywords:Epithelia, cancer, compartmental modelling, individual-based modelling, multiscale modelling, continuum modelling, inference.
Subjects:A - C > Biology and other natural sciences
Research Groups:Centre for Mathematical Biology
ID Code:1892
Deposited By: Philip Maini
Deposited On:27 Aug 2015 07:11
Last Modified:27 Aug 2015 07:11

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