The Mathematical Institute, University of Oxford, Eprints Archive

Differential recruitment of the sensorimotor putamen and frontoparietal cortex during motor chunking in humans

Wymbs, N F and Bassett, D S and Mucha, P J and Porter, M A and Grafton, S T (2012) Differential recruitment of the sensorimotor putamen and frontoparietal cortex during motor chunking in humans. Neuron, 74 (5). pp. 936-946.

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Abstract

Motor chunking facilitates movement production by combining motor elements into integrated units of behavior. Previous research suggests that chunking involves two processes: concatenation, aimed at the formation of motor-motor associations between elements or sets of elements, and segmentation, aimed at the parsing of multiple contiguous elements into shorter action sets. We used fMRI to measure the trial-wise recruitment of brain regions associated with these chunking processes as healthy subjects performed a cued-sequence production task. A dynamic network analysis identified chunking structure for a set of motor sequences acquired during fMRI and collected over 3 days of training. Activity in the bilateral sensorimotor putamen positively correlated with chunk concatenation, whereas a left-hemisphere frontoparietal network was correlated with chunk segmentation. Across subjects, there was an aggregate increase in chunk strength (concatenation) with training, suggesting that subcortical circuits play a direct role in the creation of fluid transitions across chunks.

Item Type:Article
Subjects:A - C > Biology and other natural sciences
Research Groups:Centre for Mathematical Biology
ID Code:1803
Deposited By: Sara Jolliffe
Deposited On:22 Feb 2014 09:19
Last Modified:29 May 2015 19:29

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