The Mathematical Institute, University of Oxford, Eprints Archive

Non-linear modeling of active biohybrid materials

Paetsch, C. and Dorfmann, L. (2012) Non-linear modeling of active biohybrid materials. Journal of Nonlinear Mechanics . (Submitted)

[img]
Preview
PDF
466kB

Abstract

Recent advances in engineered muscle tissue attached to a synthetic substrate motivates the development of appropriate constitutive and numerical models. Applications of active materials can be expanded by using robust, non-mammalian muscle cells, such as those of Manduca sexta. In this study, we propose a model to assist in the analysis of biohybrid constructs by generalizing a recently proposed constitutive law for Manduca muscle tissue. The continuum model accounts (i) for the stimulation of muscle fibers by introducing multiple stress-free reference configurations for the active and passive states and (ii) for the hysteretic response by specifying a pseudo-elastic energy function. A simple example representing uniaxial loading-unloading is used to validate and verify the characteristics of the model. Then, based on experimental data of muscular thin films, a more complex case shows the qualitative potential of Manduca muscle tissue in active biohybrid constructs.

Item Type:Article
Subjects:D - G > General
Research Groups:Oxford Centre for Collaborative Applied Mathematics
ID Code:1661
Deposited By: Peter Hudston
Deposited On:09 Feb 2013 09:42
Last Modified:29 May 2015 19:21

Repository Staff Only: item control page