The Mathematical Institute, University of Oxford, Eprints Archive

Theoretical insights into bacterial chemotaxis

Tindall, M. J. and Gaffney, E. A. and Maini, P. K. and Armitage, J. P. (2012) Theoretical insights into bacterial chemotaxis. WIREs System Biology Med, 4 (3). pp. 247-259.

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Abstract

Research into understanding bacterial chemotactic systems has become a paradigm for Systems Biology. Experimental and theoretical researchers have worked hand‐in‐hand for over 40 years to understand the intricate behavior driving bacterial species, in particular how such small creatures, usually not more than 5 µm in length, detect and respond to small changes in their extracellular environment. In this review we highlight the importance that theoretical modeling has played in providing new insight and understanding into bacterial chemotaxis. We begin with an overview of the bacterial chemotaxis sensory response, before reviewing the role of theoretical modeling in understanding elements of the system on the single cell scale and features underpinning multiscale extensions to population models.

Item Type:Article
Subjects:A - C > Biology and other natural sciences
Research Groups:Centre for Mathematical Biology
ID Code:1512
Deposited By:Philip Maini
Deposited On:24 Apr 2012 07:51
Last Modified:27 Dec 2012 21:38

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